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Journal of Drug Delivery
Volume 2015 (2015), Article ID 827859, 14 pages
http://dx.doi.org/10.1155/2015/827859
Research Article

Formulation and In Vitro Evaluation of Bilayer Tablets of Nebivolol Hydrochloride and Nateglinide for the Treatment of Diabetes and Hypertension

1Vishnu Institute of Pharmaceutical Education and Research, Vishnupur, Narsapur, Medak, Telangana 502313, India
2Department of Pharmaceutics, Pulla Reddy Institute of Pharmacy, Annaram, Hyderabad 502313, India

Received 27 September 2014; Revised 8 December 2014; Accepted 8 December 2014

Academic Editor: Sri Rama K. Yellela

Copyright © 2015 Harika Ryakala et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. R. A. King, J. I. Rotter, and A. G. Motulsky, The Genetic Basis of Common Diseases, Oxford University Press, Oxford, UK, 1992.
  2. M. Epstein and J. R. Sowers, “Diabetes mellitus and hypertension,” Hypertension, vol. 19, no. 5, pp. 403–418, 1992. View at Publisher · View at Google Scholar · View at Scopus
  3. I. Hasan and S. Khatoon, “Prevalence of diabetes mellitus and obesity among population of Sultanpur kunhari and its surrounding area, Haridwar Uttarakhand,” International Research Journal of Pharmacy, vol. 3, pp. 226–229, 2012. View at Google Scholar
  4. A. H. Zargar, A. A. Wani, B. A. Laway et al., “Prevalence of diabetes mellitus and other abnormalities of glucose tolerance in young adults aged 20-40 years in North India (Kashmir Valley),” Diabetes Research and Clinical Practice, vol. 82, no. 2, pp. 276–281, 2008. View at Publisher · View at Google Scholar · View at Scopus
  5. G. F. H. Ehud, E. Z. Messerlib, and A. Tenenbaum, “Hypertension and diabetes,” in Cardiovascular Diabetologyclinical , Metabolic and Inflammatory Facets, vol. 45 of Advances in Cardiology, pp. 82–106, Karger, Basel, Switzerland, 2008. View at Google Scholar
  6. R. A. de Boer, A. A. Voors, and D. J. van Veldhuisen, “Nebivolol: third-generation β-blockade,” Expert Opinion on Pharmacotherapy, vol. 8, no. 10, pp. 1539–1550, 2007. View at Publisher · View at Google Scholar · View at Scopus
  7. A. Veverka, D. S. Nuzum, and J. L. Jolly, “Nebivolol: a third-generation β-adrenergic blocker,” Annals of Pharmacotherapy, vol. 40, no. 7-8, pp. 1353–1360, 2006. View at Publisher · View at Google Scholar · View at Scopus
  8. O. Kamp, G. T. Sieswerda, and C. A. Visser, “Comparison of effects on systolic and diastolic left ventricular function of Nebivolol versus Atenolol in patients with uncomplicated essential hypertension,” American Journal of Cardiology, vol. 92, no. 3, pp. 344–348, 2003. View at Publisher · View at Google Scholar · View at Scopus
  9. A. C. Pessina, “Metabolic effects and safety profile of nebivolol,” Journal of Cardiovascular Pharmacology, vol. 38, no. 3, pp. S33–S35, 2002. View at Google Scholar · View at Scopus
  10. C. J. Dunn and D. Faulds, “Nateglinide,” Drugs, vol. 60, no. 3, pp. 607–615, 2000. View at Publisher · View at Google Scholar · View at Scopus
  11. P. Norman and X. Rabasseda, “Nateglinide: a structurally novel, short-acting, hypoglycemic agent,” Drugs of Today, vol. 37, no. 6, pp. 411–426, 2001. View at Publisher · View at Google Scholar · View at Scopus
  12. J. Cooper and C. Gunn, “Powder flow and compaction,” in Tutorial Pharmacy, S. J. Carter, Ed., pp. 211–233, CBS Publishers and Distributors, Delhi, India, 1986. View at Google Scholar
  13. J. R. Patel, B. A. Patel, D. G. Patel, D. S. Patel, and V. B. Patel, “Formulation and evaluation of oral controlled drug delivery system for a model anti diabetic drug metformin,” International Journal of Current Pharmaceutical Research, vol. 3, pp. 37–39, 2011. View at Google Scholar
  14. M. Rangapriya, V. Manigandan, R. Natarajan, and K. Mohan Kumar, “Formulation and evaluation of floating tablets of Pioglitazone hydrochloride,” International Journal of Pharmaceutical and Chemical Sciences, vol. 1, pp. 1048–1054, 2012. View at Google Scholar
  15. V. Thanda, S. Firoz, C. Yerram, A. Vikram, S. K. Divya, and K. T. Murali, “Design and characterisation sustained release matrix tablets of Repaglinide using natural polymers,” International Journal of Pharmacy, vol. 2, pp. 73–83, 2012. View at Google Scholar
  16. D. Vamshi, P. Laxmi Madhuri, and G. Tuljarani, “Method development and validation of indapamide and nebivolol hydrochloride by rp-hplc method,” International Journal of Research In Pharmaceutical and Nano Sciences, vol. 2, no. 6, pp. 798–810, 2013. View at Google Scholar
  17. Indian Pharmacopoeia, Indian Pharmacopoeia, vol. 3, Worldwide Book Service, 2014.
  18. United States Pharmacopoeia 34, vol. 3, pp. 3611–3614, 2011.
  19. G. H. Kumar, K. Jaganathan, R. S. Kumar, and P. Peruma, “Formulation and in-vitro evaluation of bilayer floating tablets of Metformin hydrochloride and Sitagliptin phosphate,” International Journal of Advanced Pharmaceutics, vol. 2, no. 2, pp. 64–81, 2012. View at Google Scholar
  20. D. Rohini, S. Alexandar, and M. J. N. Chandrasekar, “Preparation and in vitro evaluation of sustained release tablet formulations of metformin HCL,” Asian Journal of Pharmaceutical and Clinical Research, vol. 5, no. 1, pp. 45–48, 2012. View at Google Scholar · View at Scopus
  21. K. Venkateswarlu and A. Shanthi, “Formulation and evaluation of sustained release glipizide matrix,” IOSR Journal of Pharmacy and Biological Sciences (IOSRJPBS), vol. 2, no. 5, pp. 17–23, 2012. View at Publisher · View at Google Scholar
  22. P. Shirse, “Formulation and evaluation of bilayered tablets of HP-β-cyclodextrin complexed glimepiride with metformin hydrochloride for immediate and sustain release,” International Journal of Pharmacy and Biological Sciences, vol. 3, no. 3, pp. 148–160, 2012. View at Google Scholar · View at Scopus
  23. C. H. Harika, Y. R. J. Rao, S. K. Gousia Parvin, and S. S. Sastry, “Formulation and evaluation of immediate release tablets of Nebivolol Hydrochloride,” International Journal of Pharmaceutical Archives, vol. 2, no. 11, pp. 251–258, 2013. View at Google Scholar
  24. L. Preethi, B. Sree Giri Prasad, and R. Pranitha, “Formulation and evaluation of immediate release tablets of Nebivolol hydrochloride,” Journal of Global Trends in Pharmaceutical Sciences, vol. 5, no. 3, pp. 1790–1796, 2014. View at Google Scholar
  25. M. Sudhakar, V. Umesh Rao, and N. Samalla, “Development and optimization of paracetamol immediate release and aceclofenac control release bilayer tablet,” American Journal of Advanced Drug Delivery, vol. 2, pp. 98–103, 2013. View at Google Scholar