Table 12: Results of stability study of optimized batch (F22).

Evaluation parametersInitiallyAfter 30 days

Weight variation ()430 ± 1.2429 ± 3.3
Diameter (mm)10.0 ± 0.0510.0 ± 0.05
Thickness (mm)5.0 ± 0.25.0 ± 0.1
Hardness (kg/cm2)6.8 ± 0.26.7 ± 0.5
Friability (%)0.490.52
% drug content97.2 ± 3.897.0 ± 1.3
1 (% drug release at 1 hr)28.56%30.07%
2 (% drug release at 6 hr)61.81%60.37%
3 (% drug release at 12 hr)95.72%93.88%