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Table 10

Dry powder coated lactose incorporated DPI formulations.

Drug	Coating mechanism and coating time (min)	Key ingredients	PSD (μm)	Device and flow rate (l/min)	% FPF	References
SS	Wurster Fluidized Bed and 180	Pharmatose 200 M and aqueous HPMC solution	81.80	Jethaler and 60		[100]
SS	Theta-Composer® and 10	Pharmatose 200 M and MgSt (10%)		Jethaler and 30	~40.00	[99]
SS	Vortex-Mixer; and 60	Pharmatose 200 M and MgSt (2%)	87.50	Jethaler and 60		[101]
SS	Theta-Composer and 10	Pharmatose 200 M; and sucrose tristearate (10%)		Jethaler and 60		[102]
TNRA	Rotor-type powder mixer (Mechanofusion) and 15	Pharmatose 325 M and sucrose stearate (1%)	90	Jethaler and 30	20.90	[103]
TNRA	Rotor-type powder mixer (Mechanofusion) and 15	Pharmatose 325 M and MgSt (2%)		Jethaler and 30	34.60	[103]
SS	Rotor-type powder mixer (Mechanofusion)	MgSt (5%)	-	Monodose inhaler and 60	69.00	[104]
Salmeterol xinafoate	Rotor-type powder mixer (Mechanofusion)	MgSt (5%)	-	Monodose inhaler and 60	73.10	[104]

SS: salbutamol sulphate; MgSt: magnesium stearate; TNRA: triple neurokinin receptor antagonist; and FPF: fine particle fraction.