Review Article

Imagine the Superiority of Dry Powder Inhalers from Carrier Engineering

Table 5

Spray-dried lactose loaded DPI formulations.

DrugMethodKeyPSDDevice and flow% FPFReferences
ingredients(μm)rate (l/min)

Pranlukast hydrateSDPharmatose 200 M and Pharmatose 325 M<90Spinhaler® and 60[35]
Human serum albuminSDAlbuminlactoseDPPC (30 : 10 : 60)6.50Spinhaler and 28.3[36]
SSSDLactochem crystals77.72Cyclohaler and 60[37]
BudesonideSDα-LM>230aifun®[38]

aifun is a multiple dose, reservoir-based DPI. DPPC: dipalmitoyl phosphatidylcholine; FPF: fine particle fraction.