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Experimental Diabetes Research
Volume 2007 (2007), Article ID 76271, 6 pages
Research Article

Diabetic Retinopathy in Native and Nonnative Canadians

1Faculty of medicine, University of Calgary, # 238-4411 16th Ave NW, Calgary, AB T3B 0M3, Canada
2Grant MacEwan College, 5-225K City Centre Campus, Edmonton, AB T5J 4S2, Canada
3Department of community health, University of Calgary, 29th St Northwest, Calgary, AB T2N 1N4, Canada

Received 18 March 2007; Accepted 12 July 2007

Academic Editor: Subrata Chakrabarti

Copyright © 2007 Stuart A. Ross et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


High prevalence rates of type 2 diabetes are being observed in native Canadian communities. It is believed that native populations have a higher prevalence rate of vascular complications than nonnatives. The Southern Alberta Study of Diabetic Retinopathy (DR) examined the prevalence and incidence of DR and associated metabolic abnormalities in native and nonnative subjects. Prevalence rates of DR in type 2 diabetic native and nonnative subjects were identical, with a prevalence rate of 40%. Native subjects with retinopathy, however, tended to have more advanced changes of retinopathy compared to the nonnative subjects. Key factors such as A1c, blood pressure, duration of diabetes, and lipid values were not significantly different between the two cohorts. These data indicate that ethnicity does play a role in the development and severity of DR but potential risk factors that may affect the development of retinopathy are not significantly different between native and nonnative groups.