Human Islet Amyloid Polypeptide Transgenic Mice: In Vivo and Ex Vivo Models for the Role of hIAPP in Type 2 Diabetes Mellitus
Figure 4
Detection of islet amyloid in islet of Langerhans isolated from an hIAPP transgenic mouse,
and cultured in medium with a high glucose concentration. Frozen section of a gelatine-embedded
islet was stained with the amyloid-specific dye Congo red and visualized with
light microscopy (a) and fluorescence microscopy (b), respectively.