Research Article

Human Islet Amyloid Polypeptide Transgenic Mice: In Vivo and Ex Vivo Models for the Role of hIAPP in Type 2 Diabetes Mellitus

Figure 4

Detection of islet amyloid in islet of Langerhans isolated from an hIAPP transgenic mouse, and cultured in medium with a high glucose concentration. Frozen section of a gelatine-embedded islet was stained with the amyloid-specific dye Congo red and visualized with light microscopy (a) and fluorescence microscopy (b), respectively.
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(a)
697035.fig.004b
(b)