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Experimental Diabetes Research
Volume 2008, Article ID 728763, 13 pages
http://dx.doi.org/10.1155/2008/728763
Research Article

Islet Specific Wnt Activation in Human Type II Diabetes

1Development and Aging Program, Burnham Institute for Medical Research, 10901 N. Torrey Pines Road, La Jolla, CA 92037, USA
2Department of Pediatrics, University of California San Diego, 9500 Gilman Dr, MC 0816, La Jolla, CA 92093, USA
3Moores Cancer Center, University of California San Diego, La Jolla, CA 92093, USA
4Sanford Children's Health Research Center, Burnham Institute for Medical Research, 10901 N. Torrey Pines Road, CA 92037, USA

Received 3 June 2008; Accepted 7 October 2008

Academic Editor: Anjan Kowluru

Copyright © 2008 Seung-Hee Lee et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

The inverse expression pattern of γ- and ß-catenin in normal adult and fetal human pancreas. Supplementary Figure 2 illustrates the expression pattern of pGSK3ß in the normal and Type II pancreas, revealing that there is higher expression in Type II than in normal islets.

  1. Figure 1
  2. Figure 2