C-Peptide and Its C-Terminal Fragments Improve Erythrocyte Deformability in Type 1 Diabetes Patients
Figure 2
Erythrocyte elongation index (EI) (%) ± SD for erythrocytes from healthy controls and type 1 diabetes
patients. The latter cells were incubated with C-peptide, hexapeptide (HP), and
pentapeptide (PP) from the C-terminal region of C-peptide as well as a middle fragment (MF)
and scrambled peptide (SCR, control). Results for combined incubation with PP
and oubain or EDTA are also shown. Data are obtained at the shear stress level 1.2 Pa. versus untreated
erythrocytes from type 1 diabetes patients.