Structural and Ultrastructural Analysis of Cerebral Cortex, Cerebellum, and Hypothalamus from Diabetic Rats

Table 2

Percentages of mitochondrial alterations in diabetes.

	Control	Diabetes	𝑃 values
Cerebrum
Cellular body
VM^a	2.1 ± 2.4	25.7 ± 9.81	𝑃=.01
SM^b	4.73 ± 1.97	29.4 ± 8.9	𝑃=.01
Total	6.79 ± 1.8	55.13 ± 5.5	𝑃=.005
Neuropil
VM	2.0 ± 2.3	27.9 ± 4.11	𝑃=.0004
SM	4.60 ± 3.3	14.65 ± 4.24	𝑃<.04
Total	6.6 ± 2.9	36.16 ± 15.78	𝑃<.04
Cerebellum
Cellular body
VM	5.13 ± 3.5	28.8 ± 2.2	𝑃<.006
SM	4.45 ± 1.8	20.5 ± 4.6	𝑃<.006
Total	9.55 ± 4.97	49.32 ± 5.79	𝑃<.006
Neuropil
VM	3.3 ± 2.8	34.3 ± 1.74	𝑃<.002
SM	1.68 ± 1.73	13.16 ± 7.66	𝑃<.002
Total	4.95 ± 3.6	47.42 ± 8.8	𝑃<.002
Hypothalamus
Cellular body
VM	3.85 ± 1.06	29.35 ± 12.31	𝑃=.02
SM	3.83 ± 3.06	21.28 ± 5.07	𝑃<.005
Total	7.65 ± 4.06	50.61 ± 8.24	𝑃<.005
Neuropil
VM	6.03 ± 2.25	25.63 ± 8.67	𝑃<.04
SM	1.9 ± 0.74	9.0 ±3.97	𝑃<.04
Total	7.93 ± 2.02	34.64 ± 11.84	𝑃<.04

aVM: vacuolated mitochondria; bSM: swollen mitochondria.