Clinical Study

C-Reactive Protein and Gamma-Glutamyltransferase Concentrations in Relation to the Prevalence of Type 2 Diabetes Diagnosed by Glucose or HbA1c Criteria in Chinese Adults in Qingdao, China

Table 1

Baseline characteristics of participants according to diabetes status defined according to either glucose or HbA1c criteria in individuals without a prior history of diabetes.

FPG 7.0 mmol/L and/or 2hPG 11.1 mmol/LHbA1c 6.5%
MenWomenMenWomen
NoYesNoYesNoYesNoYes

Number (%)1014 (86.9)153 (13.1)1423 (88.6)184 (11.4)1044 (89.5)123 (10.5)1446 (90.0)161 (10.0)
Age (years)48.452.848.355.349.248.449.049.4
(47.5, 49.3)(52.0, 53.6)*(48.0, 48.6)(54.6, 56.0)*(48.9, 49.5)(47.5, 49.3)(48.7, 49.3)(48.5, 50.3)
School years 9 (%)45.343.436.525.3*46.430.9*36.817.2*
Current smoking (yes, %)47.147.71.32.246.452.01.50.7
Alcohol-drinking (yes, %)48.849.01.60.548.551.21.60.7
Family history of diabetes (yes, %)12.324.2*16.422.8*13.913.013.711.9
Occupational activity (%)
Light15.114.014.715.915.412.213.212.0
Moderate46.452.761.864.048.041.545.447.0
Heavy38.533.323.520.136.646.341.451.0
Body mass index (kg/m2)25.626.125.627.025.725.925.826.1
(25.4, 25.8)(25.5, 26.7)*(25.5, 25.8)(26.5, 27.5)*(25.5, 25.9)(25.3, 26.5)(25.6, 26.0)(25.6, 26.7)
Waist circumference (cm)87.1 (86.5, 87.7)89.6 (88.0, 91.1)*81.5 (81.0, 81.9)86.4 (84.9, 87.8)*87.4 (96.8, 87.9)87.7 (85.8, 89.5)81.8 (81.4, 82.3)85.2 (83.5, 86.8)*
Systolic blood pressure (mmHg)132140129138133134131131
(131, 133)(137, 143)*(128,130)(135, 141)*(132,134)(132,136)(131, 132)(128, 134)
Diastolic blood pressure (mmHg)87 (86, 88)90 (88, 92)*83 (82,84)87 (86, 88)*87 (86, 88)89 (86, 91)84 (83, 85)84 (82, 86)
Fasting plasma glucose (mmol/L)5.33 (5.29, 5.38)8.00 (7.55, 8.46)*5.37 (5.34, 5.42)7.66 (7.25, 8.08)* 5.59 (5.53, 5.65)6.44 (6.11, 6.77)*5.58 (5.53, 5.63)6.13 (5.90, 6.36)*
2 hours post-load plasma glucose (mmol/L)6.23 (6.14, 6.33)13.2 (12.4, 14.1)*6.63 (6.55, 6.71)13.20 (12.44,13.96)* 6.77 (6.62, 6.91)9.76 (8.69, 10.83)*7.12 (6.99, 7.24)9.78 (8.81, 10.75)*
Fasting insulin (  mol/L)30.7237.1539.9849.6628.1132,4737.4142.07
(29.67, 31.77)(35.45, 38.85)*(38.85, 41.11)(48.36, 50.96)*(25.68, 30.54)(31,16, 33.78)*(36.14, 38.68)(40.18, 43.06)*
Low density lipoprotein cholesterol (mmol/L)2.96 3.20 2.983.372.973.123.042.94
(2.90, 3.01)(3.03, 3.36)*(2.93, 3.03)(3.22, 3.52)*(2.91, 3.03)(2.94, 3.30)(2.99, 3.08)(2.78, 3.11)
High density lipoprotein cholesterol (mmol/L)1.621.61 1.671.591.611.721.661.71
(1.60, 1.65)(1.54, 1.69)(1.65,1.69)(1.52, 1.66)*(1.58,1.64)(1.65, 1.80)*(1.64,1.68)(1.64,1.76)
Triglycerides (mmol/L)1.371.49 1.151.481.451.421.221.24
(1.33, 1.42)(1.34,1.64)*(1.11, 1.18)(1.32,1.60)*(1.40,1.51)(1.19, 1.65)(1.17,1.26)(1.03, 1.45)
Total cholesterol (mmol/L)5.225.63 5.175.735.245.435.255.15
(5.16, 5.28)(5.46, 5.81)*(5.12, 5.22)(5.57, 5.89)*(5.18, 5.31)(5.23, 5.63)*(5.19, 5.29)(4.97, 5.34)
C-reactive protein (mg/dl)§0.871.26 0.721.260.910.940.760.90
(0.76, 0.98)(1.08, 1.44)*(0.66, 0.78)(1.06,1.46)*(0.78,1.04)(0.60, 11.14)(0.70, 0.82)(0.88, 0.92)*
Alanine aminotransferase (U/L)13.116.911.013.113.713.511.211.7
(12.4, 13.9)(14.8, 18.9)*(10.4, 11.6)(11.2, 14.9)*(12.9,14.4)(11.2, 15.8)(10.5, 11.7)(9.6, 13.7)
Gamma-glutamyltransferase (U/L)§28.641.415.5 23.629.930.1 16.217.4
(26.5, 30.7)(37.2, 45.6)*(15.2, 15.8)(22.0, 25.2)*(27.8, 32.0)(27.3, 32.9)(15.8, 16.6)(16.0, 18.8)

Data are age-adjusted mean (95% confidence interval) or percentages as indicated. , diabetes versus nondiabetes by the same criteria within the same gender. §Geometric mean (95% CI). With missing data .