Development of a Nongenetic Mouse Model of Type 2 Diabetes
Figure 9
Relative islet volume and total islet mass on the final day of the trial. (a) Relative islet volume and (b) total islet mass. Male, retired breeder (6 mo.) C57BL/6 mice were used for this study. Values represent mean ± SEM (–8). *, versus pancreas head region in mice receiving the same treatment (interaction of pancreas region × treatment), # versus respective non-STZ injected group (interaction of pancreas region × treatment in panel (a) and main effect of treatment in panel (b).
(a) Relative islet volume in head and body of pancreas
