Exercise Increases Insulin Content and Basal Secretion in Pancreatic Islets in Type 1 Diabetic Mice
Figure 5
Insulin content per islet. (a) Exercise significantly improved the insulin content per islet between the two diabetic groups (). (b) Immunohistochemical staining showing the intensity of insulin-immunoreactive (red) cells in islets from pancreatic sections. (Scale bar: 50 μm.) (c) Quantification of the intensity of insulin-positive staining per islet in pancreatic sections. Exercise improved the total insulin staining intensity per islet significantly (**). (d) The intensity of insulin-positive staining was calculated per β-cell, and exercise significantly improved the insulin content per cell (**). Control ; sedentary diabetic ; exercised diabetic .