Research Article

Angiotensin II Type II Receptor Deficiency Accelerates the Development of Nephropathy in Type I Diabetes via Oxidative Stress and ACE2

Figure 1

Physiological parameters measurement in 3 groups (control (open bar), diabetic (black bar), and insulin-treated diabetic (shadowed bar)) of both WT and AT2RKO male mice at the age of 16 weeks. (a) Gross body weight (BW, g); (b) Food consumptions (g/day); (c) KW/BW ratio; (d) blood glycemic concentration (mM). *P ≤ 0.05; **P ≤ 0.01; NS, non significant.
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(a) BW in 16-week-old mice
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(b) 16-week-old mice
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(c) Ratio of KW/BW in 16-week-old mice
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(d) Blood glycemia in 16-week-old mice