Research Article

Altered Expression of Somatostatin Receptors in Pancreatic Islets from NOD Mice Cultured at Different Glucose Concentrations In Vitro and in Islets Transplanted to Diabetic NOD Mice In Vivo

Figure 3

Syngeneic pancreatic islets in groups of 200 islets were transplanted beneath the kidney capsule, and the animal was sacrificed on day 3 after transplantation. A representative graft in a transplanted diabetic NOD mouse stained for insulin (green, (a)–(e)) coexpressing sst1-5 (yellow, (f)–(j)). (k)–(o) show a representative graft in transplanted diabetic NOD mice single stained with sst1-5-specific antibodies. Bar = 50 μm.
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