Neurovascular Interaction and the Pathophysiology of Diabetic Retinopathy
Figure 7
Real-time RT-PCR measurements of iNOS expression in the retinas of diabetic and 5-methyl-I4AA-treated rat eyes. The amount of RNA in each sample was determined by the value of Ct, the cycle number for the amount of PCR product needed to reach the fluorescence threshold. When normalized to L7 expression, a housekeeping gene of 60S ribosomal protein, the expression level of iNOS in diabetic retina was significantly reduced (i.e., a higher ΔCt value) after treatment with the GABAC receptor agonist.
