The Effect of Metformin on the Myocardial Tolerance to Ischemia-Reperfusion Injury in the Rat Model of Diabetes Mellitus Type II

Table 1

Pre- and postischemic values of heart rate (HR, beats per minute) in different groups.

	Controls	Controls + metformin	T2DM	T2DM + metformin
Preischemic HR, beats per min	239 ± 48	254 ± 33	251 ± 32	249 ± 32
Postischemic HR:
10 min	219 ± 39	235 ± 74	203 ± 37	278 ± 90
20 min	205 ± 34	252 ± 63	218 ± 22	286 ± 68
30 min	210 ± 45	262 ± 71	239 ± 51	268 ± 80
40 min	202 ± 59	268 ± 71	220 ± 34	270 ± 65
50 min	193 ± 45	233 ± 56	214 ± 36	266 ± 75
60 min	198 ± 50	249 ± 68	238 ± 39	269 ± 61