Research Article

Inhibition of Aldose Reductase by Gentiana lutea Extracts

Figure 4

Stereoview of ALR2 docked with gentiopicroside. (a) Gentiopicroside docked into the active site of ALR2 and extended towards hydrophobic pocket.ā€‰ā€‰(b) Gentiopicroside docked into active site of ALR2 and depicts its hydrophobic interactions with Trp-219, Phe-122, and Leu-301 (dotted line).
147965.fig.004a
(a)
147965.fig.004b
(b)