Differential Proteome Profiling Using iTRAQ in Microalbuminuric and Normoalbuminuric Type 2 Diabetic Patients
Figure 8
ROC curves for three candidate biomarkers and the 3-marker panel. MRM validation was performed for (a) alpha-1-antitrypsin, (b) alpha-1-acid glycoprotein 1, (c) prostate stem cell antigen, and (d) their combination, generating AUC values of 0.849, 0.873, and 0.825, respectively, whereas the combination resulted in a merged AUC of 0.921.