Spontaneous Periodontitis Development in Diabetic Rats Involves an Unrestricted Expression of Inflammatory Cytokines and Tissue Destructive Factors in the Absence of Major Changes in Commensal Oral Microbiota
Figure 2
Increased number of RAGE-positive cells in diabetic groups. Histological sections of periodontal tissues were submitted to immunohistochemical analyses for RAGE after 1, 3, 6, 9, and 12 months of diabetes induction. The results are presented as mean ± SD of immunoreactive cells per mm2 in 3 semiserial section of each animal, *, one-way analysis of variance (ANOVA) followed by Tukey’s test.
