Research Article

Comparison of Oxidant/Antioxidant, Detoxification Systems in Various Tissue Homogenates and Mitochondria of Rats with Diabetes Induced by Streptozocin

Table 1

Evaluation of parameters measured in both group by tissue types.

MeasurementLung X ± SLiver X ± SKidney X ± SHeart X ± S

MDA (nmol/mL)
Control3,81 ± 1,1§3,22 ± 0,7 5,22 ± 0,8ξ1,29 ± 0,4ξ
Diabetic3,22 ± 3,19,01 ± 7,8*3,30 ± 1,50,50 ± 0,4*

TAS (mmol trolox Equiv/L)
Control0,423 ± 0,540,406 ± 0,210,376 ± 0,100,143 ± 0,03
Diabetic0,19 ± 0,060,53 ± 0,280,45 ± 0,280,18 ± 0,04

TOS (μmol H2O2 Equiv/L)
Control7,75 ± 10,44,46 ± 1,26,40 ± 2,42,53 ± 0,9
Diabetic2,22 ± 0,03#6,29 ± 1,05#4,59 ± 0,78# 1,49 ± 0,6#

OSİ (%)
Control16,83 ± 2,3513,12 ± 6,7016,97 ± 4,1217,35 ± 3,42
Diabetic12,05 ± 3,415,82 ± 11,412,49 ± 6,998,07 ± 1,44

PON (U/L)
Control4,33 ± 3,2*4,33 ± 1,5*9,33 ± 0,5*7,66 ± 1,5
Diabetic6,00 ± 3,06,00 ± 4,38,00 ± 1,07,33 ± 1,5

Arylesterase (U/L)
Control4365,0 ± 410,74347,6 ± 738,54093,3 ± 359,14068,3 ± 380,6
Diabetic4785,0 ± 111,84088,3 ± 541,04350,0 ± 172,44249,0 ± 483,0

GST (U/mgPrt)
Control0,0032 ± 0,0020,0547 ± 0,0400,0073 ± 0,0040,0062 ± 0,003
Diabetic0,0011 ± 0,0010,0238 ± 0,0200,0020 ± 0,0030,0173 ± 0,029

Catalase (U/mgPrt)
Control0,545 ± 0,070,1176 ± 0,040,0371 ± 0,020,0188 ± 0,01
Diabetic0,012 ± 0,0030,0665 ± 0,0290,0381 ± 0,0360,0488 ± 0,04

* , § , # .