Differential Changes of Aorta and Carotid Vasodilation in Type 2 Diabetic GK and OLETF Rats: Paradoxical Roles of Hyperglycemia and Insulin
Protein expression of endothelial nitric oxide synthase (eNOS) and inducible heme oxygenase (HO-1) after hyperglycemia/hyperosmotic stimulation. Hyperosmolarity was made by adding extra glucose or mannitol (50 mmol/L) into Krebs-Henseleit Buffer with a final osmolarity of 350 mOsm/L (Krebs-Henseleit Buffer, 300 mOsm/L). Data are presented as mean ± SEM, . ** versus respective controls.
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