Differential Changes of Aorta and Carotid Vasodilation in Type 2 Diabetic GK and OLETF Rats: Paradoxical Roles of Hyperglycemia and Insulin

Table 2

Basic data of nondiabetic control Long-Evans Tokushima Otsuka rats (LETO) and diabetic Otsuka Long-Evans Tokushima Fatty rats (OLETF).

	3 months		12 months
	LETO	OLETF	LETO	OLETF
Body weight (BW), g	377±6	478±8 **	678±26	659±32
Systolic blood pressure, mmHg	155±12	145±5	148±5	150±3
Heart rate, beat/min	406±12	411±16	358±6	383±14
Total cholesterol, mmoL/L	1.97±0.06	2.35±0.08 **	3.13±0.19	5.88±0.64 **
LDL-cholesterol, mmoL/L	0.13±0.01	0.14±0.01	0.25±0.02	0.69±0.12 **
HDL-cholesterol, mmoL/L	0.77±0.02	0.94±0.03 **	0.87±0.04	1.43±0.14 **
Triglyceride, mmoL/L	0.24±0.07	0.63±0.06 **	0.33±0.04	2.03±0.29 **

* 𝑃<0.05, **𝑃<0.01 versus respective age-matched LETO controls. Data are mean ± SEM, 𝑛=8.