Antioxidant Sol-Gel Improves Cutaneous Wound Healing in Streptozotocin-Induced Diabetic Rats
Figure 6
Effect of antioxidant sol-gel on collagen expression and collagen content at 14th day. Masson’s trichrome staining of collagen in the saline control (a), Pluronic F127 sol (b), saline plus vitamin C (c), and Pluronic F127 plus vitamin C (d). The mean score of blue stain is displayed in (e). Four groups are significantly different when compared with Kruskal-Wallis test and posttest comparing all pairs of columns. Significant blue stain was demonstrated in an order of FC > SC > F > S. Increased hydroxyproline content was consistently increased in an order of FC > SC > F > S 14 days after wounding (f). Data are expressed as mean ± SEM. *P < 0.05 when compared to saline group. S: saline control; F: Pluronic F127; SC: saline plus vitamin C; FC: Pluronic F127 plus vitamin C. Original magnifications taken at ×200.
