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Experimental Diabetes Research
Volume 2012, Article ID 548732, 12 pages
http://dx.doi.org/10.1155/2012/548732
Review Article

Emerging Pharmacotherapies for Diabetic Macular Edema

1Department of Ophthalmology, Baylor College of Medicine, 7200-B Cambridge Street, Houston, TX 77030, USA
2Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, 311 9th Street North, No. 100, Naples, FL 34102, USA
3Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, 900 Northwest 17th Street, Miami, FL 33136, USA

Received 6 August 2011; Revised 27 October 2011; Accepted 27 October 2011

Academic Editor: R. G. Tilton

Copyright © 2012 Golnaz Javey et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [14 citations]

The following is the list of published articles that have cited the current article.

  • Karla C. F. Bordon, Marcio G. Perino, Jose R. Giglio, and Eliane C. Arantes, “Isolation, enzymatic characterization and antiedematogenic activity of the first reported rattlesnake hyaluronidase from Crotalus durissus terrificus venom,” Biochimie, vol. 94, no. 12, pp. 2740–2748, 2012. View at Publisher · View at Google Scholar
  • Poya Tababat-Khani, Lisa M. Berglund, Carl-David Agardh, Maria F. Gomez, and Elisabet Agardh, “Photocoagulation of Human Retinal Pigment Epithelial Cells In Vitro: Evaluation of Necrosis, Apoptosis, Cell Migration, Cell Proliferation and Expression of Tissue Repairing and Cytoprotective Genes,” Plos One, vol. 8, no. 8, 2013. View at Publisher · View at Google Scholar
  • X. Xin, M. Rodrigues, M. Umapathi, F. Kashiwabuchi, T. Ma, S. Babapoor-Farrokhran, S. Wang, J. Hu, I. Bhutto, D. S. Welsbie, E. J. Duh, J. T. Handa, C. G. Eberhart, G. Lutty, G. L. Semenza, S. Montaner, and A. Sodhi, “Hypoxic retinal Muller cells promote vascular permeability by HIF-1-dependent up-regulation of angiopoietin-like 4,” Proceedings of the National Academy of Sciences, vol. 110, no. 36, pp. E3425–E3434, 2013. View at Publisher · View at Google Scholar
  • Stephen G. Schwartz, Harry W. Flynn, and Ingrid U. Scott, “Intravitreal Corticosteroids in the Management of Diabetic Macular Edema,” Current Ophthalmology Reports, 2013. View at Publisher · View at Google Scholar
  • Ales Maver, Dimitar Hristovski, Thomas C. Rindflesch, and Borut Peterlin, “Integration of Data from Omic Studies with the Literature-Based Discovery towards Identification of Novel Treatments for Neovascularization in Diabetic Retinopathy,” BioMed Research International, vol. 2013, pp. 1–7, 2013. View at Publisher · View at Google Scholar
  • Fabio Patelli, Paolo Radice, and Enrico Giacomottivol. 54, pp. 164–173, 2014. View at Publisher · View at Google Scholar
  • Stephen G Schwartz, Harry W Flynn, and Ingrid U Scott, “Emerging drugs for diabetic macular edema,” Expert Opinion on Emerging Drugs, pp. 1–9, 2014. View at Publisher · View at Google Scholar
  • Pascale Massin, Tunde Peto, Jean-Claude Ansquer, Patrick Aubonnet, and for the MacuFEN Study Investigators, “Effects of Fenofibric Acid on Diabetic Macular Edema: The MacuFen study,” Ophthalmic Epidemiology, pp. 1–11, 2014. View at Publisher · View at Google Scholar
  • Christopher J. Wallick, Ryan N. Hansen, Joanna Campbell, Szilárd Kiss, Jonathan W. Kowalski, and Sean D. Sullivan, “Comorbidity and Health Care Resource Use Among Commercially Insured Non-Elderly Patients With Diabetic Macular Edema,” Ophthalmic Surgery, Lasers and Imaging Retina, vol. 46, no. 7, pp. 744–751, 2015. View at Publisher · View at Google Scholar
  • Victor H. Gonzalez, David S. Boyer, Ursula Schmidt-Erfurth, Jeffrey S. Heier, Carmelina Gordon, Matthew S. Benz, Dennis M. Marcus, Nelson R. Sabates, Robert Vitti, Husain Kazmi, Alyson J. Berliner, Yuhwen Soo, Xiaoping Zhu, Hadi Moini, Oliver Zeitz, Rupert Sandbrink, and Diana V. Do, “Microperimetric Assessment Of Retinal Sensitivity In Eyes With Diabetic Macular Edema From A Phase 2 Study Of Intravitreal Aflibercept,” Retina, vol. 35, no. 4, pp. 687–694, 2015. View at Publisher · View at Google Scholar
  • Ji Yeon Do, Young Keun Choi, Hyun Kook, Kyoung Ho Suk, In Kyu Lee, and Dong Ho Park, “Retinal Hypoxia Induces Vascular Endothelial Growth Factor through Induction of Estrogen-related Receptor γ,” Biochemical and Biophysical Research Communications, 2015. View at Publisher · View at Google Scholar
  • Soo Hyun Kwon, Jae Pil Shin, In Taek Kim, and Dong Ho Park, “Aqueous Levels of Angiopoietin-like 4 and Semaphorin 3E Correlate with Nonperfusion Area and Macular Volume in Diabetic Retinopathy,” Ophthalmology, 2015. View at Publisher · View at Google Scholar
  • Soo Hyun Kwon, Jae Pil Shin, Dong Ho Park, and In Taek Kim, “Association of plasma semaphorin 3a with phenotypes of diabetic retinopathy and nephropathy,” Investigative Ophthalmology and Visual Science, vol. 57, no. 7, pp. 2983–2989, 2016. View at Publisher · View at Google Scholar
  • Georgia Kourlaba, John Relakis, Ronan Mahon, Maria Kalogeropoulou, Georgia Pantelopoulou, Olga Kousidou, and Nikos Maniadakis, “Cost-utility of ranibizumab versus aflibercept for treating Greek patients with visual impairment due to diabetic macular edema,” Cost Effectiveness and Resource Allocation, vol. 14, no. 1, 2016. View at Publisher · View at Google Scholar