Review Article

New Experimental Models of Diabetic Nephropathy in Mice Models of Type 2 Diabetes: Efforts to Replicate Human Nephropathy

Figure 4

Podocyte loss in BTBR ob/ob mice. BTBR ob/ob mice have reduced podocyte number. (a and b) There is a reduction in podocyte number assessed by WT-1 staining, in BTBR ob/ob (a) compared with BTBR WT (b) mice. Reprinted with permission from the Journal of the American Society of Nephrology [46].
616313.fig.004a
(a)
616313.fig.004b
(b)