Journal of Diabetes Research / 2012 / Article / Fig 4

Review Article

Cardiac Insulin Resistance and MicroRNA Modulators

Figure 4

Established and putative signaling mechanisms activated by chronic alcohol consumption are superimposed on the signaling mechanisms activated by overnutrition to show how alcohol may exacerbate cardiac diseases in the setting of overnutrition. Dotted purple lines show alcohol mediated upregulation, and dotted orange lines show alcohol-induced inhibition of different signaling components.

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