Combined Transfection of the Three Transcriptional Factors, PDX-1, NeuroD1, and MafA, Causes Differentiation of Bone Marrow Mesenchymal Stem Cells into Insulin-Producing Cells
Figure 9
Glucose responses to glucose tolerance test of mice with diabetes after transplantation. The infected cells which expressed combination of PDX-1, NeuroD1, and MafA were transplanted into the livers of mice with STZ-induced diabetes, glucose tolerance test was performed at 7 (a) and 14 days (b) following transplantation, compared with a normal control and diabetes models without any treatment. Data are presented as mean ± SD.
