Mannan-Binding Lectin in Diabetic Kidney Disease: The Impact of Mouse Genetics in a Type 1 Diabetes Model

<table>Urinary albumin excretion. Urinary albumin excretion (UAE) by mouse strain: WT, diabetes WT (d-WT), MBL-KO (KO), and diabetes MBL-KO (d-KO). (a) C57BL/6JBomTac animals with mean indicated by “♦.” (b) 129S6/SvEvTac animals with “♦” indicating the median (median presented as untransformed data showed unequal variances among groups). Test statistics are indicated in plot area when significant. <svg height="15.25" id="M32" style="vertical-align:-3.276pt" version="1.1" viewbox="0 0 20.299999 15.25" width="20.299999" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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<g transform="matrix(.012,0,0,-.012,10.875,15.188)"><path d="M43 650h280q194 0 282 -85q85 -82 85 -215q0 -173 -123 -267q-107 -83 -297 -83h-236v27q65 5 79.5 19.5t14.5 77.5v402q0 45 -6 62.5t-21.5 24t-57.5 9.5v28zM213 547v-416q0 -55 24.5 -75t81.5 -20q133 0 203 86t70 214q0 80 -30 143t-88 97q-66 41 -170 41
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</svg>: diabetic change.</table>

Journal of Diabetes Research

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Figure 3

Figure 3: Mannan-Binding Lectin in Diabetic Kidney Disease: The Impact of Mouse Genetics in a Type 1 Diabetes Model 