Journal of Diabetes Research / 2012 / Article / Tab 2 / Clinical Study
Long-Term Consequences for Offspring of Paternal Diabetes and Metabolic Syndrome Table 2 Proportion of puberal state, values >95th of the entire group, and number of abnormalities according to antecedents of diabetes or metabolic syndrome in their parents compared with healthy parents.
Variable in offspring Healthy father and mother
(1) Diabetic father and healthy mother
(2) Diabetic mother and healthy father
(3) Both parents with diabetes
(4) Diabetic father and MS, healthy mother
(5) Diabetic mother and MS, healthy father
(6)
Pubertal stage
(%) Prepuber 18 (15.8) 11 (24.4) 13 (16.6) 5 (22.7) 5 (26.3) 3 (13.0)
0.41 Puber 27 (23.6) 10 (22.2) 23 (29.5) 0 (0) 4 (21.1) 4 (17.4) Postpuber 41 (35.9) 14 (31.1) 22 (28.2) 9 (40.9) 8 (42.1) 11 (47.8) Young adult 98 (87.9) 10 (22.2) 20 (25.6) 8 (36.4) 2 (10.5) 5 (21.7) Variables >95th
(%) 114 45 78 22 19 23 BMI 48 (42.1) 31 (68.9) 34 (43.6) 11 (50.0) 11 (57.9) 9 (39.1) 0.04 SBP 46 (40.3) 22 (48.9) 34 (43.6) 12 (54.5) 8 (42.1) 12 (52.2) 0.84 DBP 46 (40.3) 21 (46.6) 33 (42.3) 11 (50.0) 8 (42.1) 12 (52.2) 0.81 Glucose 34 (29.8) 22 (48.9) 34 (43.6) 10 (45.4) 9 (47.4) 12 (52.2) 0.11 Total cholesterol 41 (35.9) 23 (51.1) 38 (48.7) 11 (50.0) 14 (73.7) 12 (52.2) 0.03 HDL-Chol 32 (28.1) 12 (26.7) 29 (37.2) 7 (31.8) 8 (42.1) 12 (52.2) 0.20 Triglycerides 48 (42.1) 21 (46.6) 38 (48.7) 14 (63.6) 12 (63.1) 12 (52.2) 0.33 Number of variables <95th 2 (2-3) 4 (3-4) 3 (2-3) 3.5 (2–5) 4 (2–4) 3 (2–5) 0.009