Review Article
Cellular Dysfunction in Diabetes as Maladaptive Response to Mitochondrial Oxidative Stress
Table 3
Effects of experimental diabetes in levels of protein carbonyls.
| Tissue | Model | Effect | Reference |
| Mouse | Aorta | BKS.cg-m +/+ Lepr db/J mice versus wild type | ↑ | [9] | Hippocampus and cerebral cortex | Streptozotocin | ↑ | [10] | Kidney | Type 2 diabetic db/db versus normoglycemic wild type mouse | ↑ | [11] | Lenses | Streptozotocin | ↑ | [12] | Rat | Aorta | Goto-Kakizaki rats | ↑ | [13] | Bone | Goto-Kakizaki rats | ↑ | [14] | Brain | Galactose-induced hyperglycemia | ↑ | [15] | Brain | Goto-Kakizaki rats | ↑ | [16] | Brain | Streptozotocin | = | [17] | Heart | Streptozotocin | ↑ | [18] | Heart | Streptozotocin | ↑ | [19] | Heart | Streptozotocin | ↑ | [20] | Heart | Streptozotocin | ↑ | [21] | Heart | Streptozotocin | ↑ | [17] | Hemoglobin | Streptozotocin | ↑ | [22] | Intestinal tissue | Streptozotocin | ↑ | [23] | Kidney | Streptozotocin | ↑ | [24] | Kidney | Streptozotocin | ↑ | [18] | Kidney | Zucker obese hyperglycemic rats (ZDFn Gm-fa/fa) | ↑ | [25] | Kidney | Streptozotocin | ↑ | [26] | Kidney | Streptozotocin | ↑ | [17] | Lens proteins | Streptozotocin | ↑ | [27] | Liver | Streptozotocin | ↓ | [24] | Liver | Pregnant diabetic rats versus control rats | = | [28] | Liver | Galactose-induced hyperglycemia | ↑ | [15] | Liver | Streptozotocin | ↑ | [18] | Liver | Streptozotocin | ↑ | [29] | Liver | Streptozotocin | ↑ | [23] | Liver | Streptozotocin | ↑ | [30] | Liver | Streptozotocin | ↑ | [17] | Lung | Streptozotocin | ↑ | [31] | Pancreas | Streptozotocin | ↑ | [18] | Pancreas | Alloxan | ↑ | [32] | Pancreas | Streptozotocin | ↑ | [17] | Pancreas | Streptozotocin | ↑ | [33] | Plasma proteins | Streptozotocin | ↑ | [34] | Plasma proteins | Streptozotocin | ↑ | [35] | Plasma proteins | Streptozotocin | ↑ | [36] | Red blood cells | Streptozotocin | ↑ | [18] | Retinal Müller cells | Streptozotocin | ↑ | [37] | Skeletal muscle | Glupreclamp infusion versus control | ↑ | [38] | Skeletal muscle | Otsuka Long Evans Tokushima Fatty (OLETF) rats versus LETO rats | ↑ | [39] | Skeletal muscle (Soleus muscles) | Goto-Kakizaki rats | ↑ | [13] | Skeletal muscle (Plantaris muscle) | Obese Zucker rats versus lean Zucker rats | ↑ | [40] | Skeletal muscle | Streptozotocin | ↑ | [41] | Testis and epididymal sperm | Streptozotocin | ↑ | [42] | Vascular smooth muscle cells | Glucose incubation | ↑ | [43] | Rabbit | Heart | Alloxan | ↑ | [44] | Lens proteins and cells | In vitro incubation | ↑ | [45] |
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