Research Article
Angiotensin-Converting Enzyme Genotype and Peripheral Arterial Disease in Diabetic Patients
Table 2
Comparisons of characteristics by insertion/deletion (I/D) polymorphism of angiotensin-converting enzyme genotypes.
| | Characteristics | Angiotensin-converting enzyme genotype | | II | ID | DD |
| | (%) | 465 | 392 | 88 | | Age, years | 64.1 (11.7) | 62.8 (11.2) | 63.4 (11.0) | | Sex | | | | | Men | 219 (47.1) | 192 (49.0) | 43 (48.9) | | Women | 246 (52.9) | 200 (51.0) | 45 (51.1) | | Duration of diabetes, years | 11.8 (8.2) | 10.7 (7.9) | 10.8 (7.6) | | Body mass index, kg/m2 | 24.8 (3.6) | 24.8 (3.3) | 25.0 (3.6) | | Smoking | | | | | Never smokers | 309 (66.6) | 244 (62.2) | 58 (65.9) | | Current or former smokers | 155 (33.4) | 148 (37.8) | 30 (34.1) | | Hypertension | | | | | No | 191 (41.1) | 158 (40.3) | 37 (42.0) | | Yes | 274 (58.9) | 234 (59.7) | 51 (58.0) | | Systolic blood pressure, mmHg | 135.8 (18.1) | 133.9 (16.6) | 135.5 (19.5) | | Diastolic blood pressure, mmHg | 83.3 (9.9) | 83.2 (9.5) | 84.3 (10.7) | | Hemoglobin , % | 7.8 (1.8) | 7.9 (1.9) | 8.2 (1.9) | | Dyslipidemia | | | | | No | 167 (35.9) | 132 (33.7) | 35 (39.8) | | Yes | 298 (64.1) | 260 (66.3) | 53 (60.2) | | Total cholesterol, mg/dL | 204.3 (43.1) | 208.3 (43.8) | 199.5 (40.3) | | Ln(triglycerides), mg/dL | 5.0 (0.6) | 5.0 (0.6) | 4.9 (0.6) | | High-density lipoprotein cholesterol, mg/dL | 47.4 (13.5) | 48.9 (13.6) | 46.7 (12.9) | | Low-density lipoprotein cholesterol, mg/dL | 114.1 (34.7) | 115.4 (34.2) | 110.5 (27.6) | | Ln[lipoprotein (a)], mg/dL | 4.7 (1.2) | 4.7 (1.1) | 4.6 (1.2) | | Uric acid, mg/dL | 5.2 (2.1) | 5.3 (1.9) | 5.3 (2.1) | | Peripheral arterial disease | | | | | No | 430 (92.5) | 358 (91.3) | 76 (86.4) | | Yes | 35 (7.5) | 34 (8.7) | 12 (13.6) |
|
|
Data are expressed as mean (SD) or (percentage).
None of the above comparisons among the genotypes was statistically significant (i.e., all).
|
