Effect of Exercise on Kidney Function, Oxidative Stress, and Inflammation in Type 2 Diabetic KK-A^y Mice

Figure 6

Number of WT-1 positive cells and staining in each mouse at 20 weeks of age. WT-1 positive cells in exercised KK-𝐴^𝑦 mice were significantly maintained compared with those in the sedentary KK-𝐴^𝑦 mice and approached to those in KK mice. ^∗𝑃<0.01^†𝑃<0.001. Representative WT-1 staining in the renal cortex of sedentary KK (a), sedentary KK-𝐴^𝑦 (b), low-intensity exercised KK-𝐴^𝑦 (c), and moderate-intensity exercised KK-𝐴^𝑦 mice. (d) Images were taken at 400-fold magnification.