Journal of Diabetes Research / 2012 / Article / Tab 1

Clinical Study

The Common C49620T Polymorphism in the Sulfonylurea Receptor Gene SUR1 (ABCC8) in Patients with Gestational Diabetes and Subsequent Glucose Metabolism Abnormalities

Table 1

Clinical characteristics of the study groups and glucose metabolism, beta-cell function, and insulin resistance in baseline conditions and during the oral glucose tolerance test.

GDM (+)GDM (−)
ParameterMean ± SDMean ± SDP value
(n = 199)(n = 50)

Number of pregnancies2.2 ± 2.81.9 ± 2.1NS
Number of deliveries1.88 ± 2.81.82 ± 2.4NS
Average time since the GDM-complicated pregnancy (years)7.4 ± 0.77.8 ± 1.0NS
Age at the time of delivery (years)30.8 ± 5.729.2 ± 6.1NS
Age (years)38.4 ± 6.636.8 ± 5.6NS
Height (cm)163.3 ± 5.9164.2 ± 6.8NS
Body weight (kg)67.9 ± 15.268.7 ± 14.9NS
BMI (kg/m2)25.5 ± 5.625.4 ± 5.0NS
Waist circumference (cm)84.8 ± 13.285.0 ± 13.4NS
Hip circumference (cm)98.5 ± 11.1100.1 ± 10.7NS
WHR0.86 ± 0.090.84 ± 0.07NS
Fat tissue mass (kg)21.9 ± 10.222.6 ± 11.1NS
% of fat tissue (%)31.0 ± 8.031.2 ± 8.9NS
Lean body mass (kg)45.5 ± 6.146.1 ± 4.8NS
Mean systolic blood pressure (mm Hg)123.2 ± 17.3118.8 ± 14.8NS
Mean diastolic blood pressure (mm Hg)81.4 ± 12.079.0 ± 9.9NS
Heart rate (/min.)78.9 ± 11.580.2 ± 10.8NS
Glucose 0 (mmol/L)5.3 ± 0.74.9 ± 0.6<0.0001
Glucose 60 (mmol/L)8.3 ± 2.65.8 ± 1.9<0.0001
Glucose 120 (mmol/L)6.4 ± 2.24.8 ± 1.1<0.0001
Insulin 0 ( IU/mL)13.7 ± 8.713.7 ± 8.5NS
Insulin 60 ( IU/mL)106.8 ± 62.683.8 ± 41.10.0204
Insulin 120 ( IU/mL)74.6 ± 58.747.5 ± 30.60.0013
HbA1c (%)5.6 ± 0.45.4 ± 0.40.0083
HOMA IR1.76 ± 1.051.73 ± 1.03NS
HOMA %S72.2 ± 38.569.7 ± 27.0NS
HOMA %B125.4 ± 52.7145.7 ± 49.20.0012

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