Journal of Diabetes Research / 2012 / Article / Tab 2

Clinical Study

Stepwise Increases in Left Ventricular Mass Index and Decreases in Left Ventricular Ejection Fraction Correspond with the Stages of Chronic Kidney Disease in Diabetes Patients

Table 2

Determinants of left ventricular mass index (LVMI) in study patients.

CharacteristicsUnivariateMultivariate (forward)
Standardized coefficient PStandardized coefficient P

Age (year)0.0120.842
Male versus female0.1170.0480.211<0.001
Smoking(ever versus never)0.1260.033
Coronary artery disease0.1470.013
Cerebrovascular disease0.0240.681
Congestive heart failure0.262<0.0010.1960.001
CKD stage0.301<0.0010.262<0.001
Systolic blood pressure (mmHg)0.225<0.0010.203<0.001
Diastolic blood pressure (mmHg)0.0950.118
Pulse pressure (mmHg)0.2020.001
Body mass index (kg/m2)0.0490.413

Laboratory parameters
 Albumin (g/L)−0.321<0.001−0.1320.032
 Fasting glucose (mmol/L)0.0270.653
  HbA1c (%)−0.0520.389
 Triglyceride (Log mmol/L)−0.0340.570
 Cholesterol (mmol/L)0.0470.436
  Hemoglobin (g/L)−0.212<0.001
  Calcium (mmol/L)−0.1850.002
  Phosphate (mmol/L)0.1820.002
 Calcium-phosphorous product (mmol2/L2)0.1140.060
 Uric acid (μmol/L)0.1170.052
Proteinuria0.216<0.001

Medications
  Aspirin use (%)0.1900.001
  ACEI and/or ARB use (%)−0.1670.005
  Non-ACEI and/or ARB antihypertensive drug use (%)0.1880.001
  Statin use (%)−0.0410.502

Values expressed as standardized coefficient . Abbreviations are the same as Table 1.