Clinical Study

Impact of Insulin Resistance on Silent and Ongoing Myocardial Damage in Normal Subjects: The Takahata Study

Table 2

Comparisons of clinical characteristics of patients with and without IR.

IR (−)IR (+)Mets

Age63 ± 1063 ± 10 63 ± 10
Male659 (46.2%)169 (33.2%)* 145 (54.9%)*#
BMI21.9 ± 2.824.4 ± 3.2*26.1 ± 2.5*#
sBP132 ± 16136 ± 15*134 ± 14*
dBP78 ± 1080 ± 10*84 ± 8*#
BNP (pg/mL) 21.5 (12.1–37.4) 17.1 (9.5–30.5)*17.5 (9.4–33.6)*
TC (g/dL)197 (177–217)204 (187–226)*205 (182–229)*
TG (g/dL)81 (63–106)101 (77–128)*171 (150–224)*#
HDL (g/dL)61 ± 1458 ± 13*46 ± 12*#
LDL (g/dL)122 ± 29131 ± 28*124 ± 30*#
eGFR (mL/min/1.73 m2) 97 (82–112)98 (83–111)86 (74–102)*#
H-FABP (ng/mL)3.5 (2.6–4.6)3.6 (2.6–4.7)*3.7 (2.8–5.1)*

BMI: body mass index; BNP: brain natriuretic peptide; TC: total cholesterol; TG: triglyceride; HDLc: high density lipoprotein cholesterol; LDLc: low density lipoprotein cholesterol; H-FABP: heart type fatty acid binding protein; sBP: systolic blood pressure; dBP: diastolic blood pressure; Data are presented as mean ± S.D or median (interquartile range). *P < 0.05 versus IR (−); #P < 0.05 versus IR (+).