Increased Hypothalamic Inflammation Associated with the Susceptibility to Obesity in Rats Exposed to High-Fat Diet

Figure 1

Body weight in DIO, DIO-R, and CF groups during the 10 weeks (a) and the change over 8 weeks dietary intervention (b) was observed weekly. Body fat in each group was measured at 18th (c). Cumulative food intake (d and f), cumulative energy intake (e and g) were obtained in different periods and results expressed as mean±SEM.  *𝑃<0.05 for DIO versus DIO-R or CF; ^#𝑃<0.05 for DIO/HF versus DIO/CF. Groups sharing different letters above the bars mean statistically significant differences (𝑃<0.05), while those denoted by the same letters are insignificant. DIO: dietary induced obesity; DIO-R: dietary induced obesity resistant; CF: chow food; DIO/HF: DIO on HF; DIO/CF: DIO on CF; DIO-R/HF: DIO-R on HF; DIO-R/CF: DIO-R on CF.

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