Increased Hypothalamic Inflammation Associated with the Susceptibility to Obesity in Rats Exposed to High-Fat Diet

Figure 2

Relative mRNA expression of TLR4 (a), NF-κB (b), TNF-α (c), IL-1β (d), IL-6 (e), and IL-10 (f) in hypothalamus was measured by real-time PCR in each group at 18th week. All results were normalized to GAPDH and expressed as arbitrary units. Data was shown as mean±SEM. Groups sharing different letters above the bars mean statistically significant differences (𝑃<0.05), while those denoted by the same letters are insignificant. DIO: dietary induced obesity; DIO-R: dietary induced obesity resistant; CF: chow food; DIO/HF: DIO on HF; DIO/CF: DIO on CF; DIO-R/HF: DIO-R on HF; DIO-R/CF: DIO-R on CF.

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