Associations of Common Variants at APLN and Hypertension in Chinese Subjects with and without Diabetes

Table 4

Analysis for the association of haplotypes with hypertension in diabetic patients stratified by gender.

	Men					Women
Haplotype	Frequency					Frequency
			OR (95% CI)	𝑃	𝑃^∗			OR (95% CI)	𝑃	𝑃^∗
	HT	NT				HT	NT
CCA	0.45	0.42	1.16 (0.95–1.41)	0.558	0.162	0.44	0.42	1.06 (0.91–1.24)	0.160	0.460
CTG	0.32	0.32	0.99 (0.81–1.23)	0.278	0.972	0.32	0.33	0.98 (0.84–1.16)	0.464	0.867
TTA	0.18	0.20	0.89 (0.69–1.15)	0.319	0.371	0.17	0.20	0.84 (0.69–1.02)	0.551	0.083
CTA	0.04	0.06	0.69 (0.45–1.07)	0.793	0.079	0.06	0.05	1.33 (0.93–1.89)	0.068	0.111

Haplotypes were constructed in the order of rs2235307, rs2235306, and rs3115759.
NT: normotensive subjects. HT: hypertensive subjects.
∗P values were adjusted for age, body mass index and diabetes duration.