ADRB3 Polymorphism Associated with BMI Gain in Japanese Men

Table 4

Multiple regression analysis for annual BMI gain and variables in Japanese men.

	Estimate	SE	𝑡 value	Pr(>|𝑡|)
Intercept	0.193	0.097	1.998	0.047*
Age	−0.005	0.002	−2.326	0.021*
Alcohol intake	0.000	0.000	−0.649	0.517
Current exercise	0.002	0.027	0.067	0.947
Working style	0.001	0.038	0.015	0.988
Smoking status	−0.053	0.028	−1.883	0.061
ADRB3 (Trp/Arg)	0.009	0.038	0.227	0.821
ADRB3 (Arg/Arg)	0.218	0.079	2.761	0.006**
LDL	0.002	0.001	3.245	0.001**

From the stepwise multiple regression analysis, age, alcohol intake, current exercise, working style, smoking status, LDL, and the ADRB3 polymorphism were selected for the final model of the predictor of BMI gain, adjusted 𝑅²=.092 (F-statistic = 3.224, 𝑃<.01).