Benidipine Protects Kidney through Inhibiting ROCK1 Activity and Reducing the Epithelium-Mesenchymal Transdifferentiation in Type 1 Diabetic Rats

Table 4

The protein expressions of p-MYPT1, ROCK1, 𝛼-SMA, and E-cadherin.

Group	𝑛	p-MYPT1	ROCK1	α-SMA	E-Cadherin
N	8	0.87 (0.72~0.95)	0.39 (0.23∼0.55)	0.11 (0.06∼0.18)	0.95±0.27
D	9	1.32 (0.93∼1.62)^★	0.93 (0.64∼1.28)^★	0.68 (0.57∼0.82)^★	0.25±0.09^★
F	9	0.86 (0.73∼1.25)^△	0.62 (0.51∼0.8)^△	0.14 (0.08∼0.19)^△	0.45±0.11^#
B	8	0.93 (0.74∼1.39)^△	0.61 (0.52∼0.9)^△	0.13 (0.08∼0.32)^△	0.44±0.10^#
𝐹 value		7.37	20.94	125.26	28.15
𝑃 value		<0.01	<0.01	<0.01	<0.05

Note: compared with N group, ^★𝑃<0.01; compared with D group, ^△𝑃<0.01, ^#𝑃<0.05.