Relationship between Oxidant/Antioxidant Markers and Severity of Microalbuminuria in the Early Stage of Nephropathy in Type 2 Diabetic Patients

Table 1

Comparison of demographic and clinical characteristics (𝑛=50 per group).

Parameters	Group 1	Group 2	Group 3	Group 4
Age (years)	54.68±6.47	55.66±5.12	56.36±3.97	56.98±2.69
Female/male	27/23	28/22	25/25	26/24
Duration of diabetes (years)	—	7.3±1.6	7.5±1.8	7.7±1.4
BMI (kg/m^2)	24.24±1.22	24.78±1.50	24.54±1.72	24.92±1.66
Triglycerides (mmol/L)	1.46±0.39	1.41±0.11	1.38±0.15	1.43±0.10
Cholesterol (mmol/L)	4.48±0.13	4.49±0.48	4.58±0.48	4.53±0.55
HDL-C (mmol/L)	1.31±0.14	1.29±0.19	1.25±0.20	1.26±0.21
LDL-C (mmol/L)	1.39±0.63	1.47±0.87	1.55±0.93	1.67±1.01
Systolic blood pressure (mmHg)	122.92±9.16	124.08±6.87	123.36±9.81	124.52±5.61
Diastolic blood pressure (mmHg)	76.90±4.13	77.10±5.13	77.72±5.64	78.04±4.62
Microalbuminuria (mg/24 h)	8.82±1.49	14.83±3.27	96.73±41.56^*,†	247.67±24.01^*,†,#
Fasting plasma glucose (mmol/L)	4.96±0.63	6.34±0.74 *	6.37±0.82 *	6.39±0.76 *
HbA1c (%)	5.93±0.74	7.11±0.50 *	7.12±0.63 *	7.12±0.61 *

Mean ± standard deviation (SD), *𝑃<.001 versus Group 1, ^†𝑃<.001 versus Group 2, and ^#𝑃<.001 versus Group 3.