Association of the Receptor for Advanced Glycation End Products Gene Polymorphisms and Circulating RAGE Levels with Diabetic Retinopathy in the Chinese Population

Table 1

Clinical characteristics of DR and NDR groups.

	DR (𝑛=372)	NDR (𝑛=668)	Statistic value
Gender (male/female)	146/226	242/426	0.334
Age (mean ± SD)	63.39 ± 10.60	62.58 ± 11.65	0.257
Diabetes duration	9.27 ± 6.78	5.56 ± 5.58	<0.001*
BMI (kg/m^2)	24.43 ± 3.47	24.54 ± 3.86	0.635
WHR	0.92 ± 0.14	0.91 ± 0.07	0.158
Systolic blood pressure (mmHg)	133.85 ± 16.48	132.08 ± 15.32	0.091
Diastolic blood pressure (mmHg)	80.62 ± 10.46	79.57 ± 9.13	0.116
FPG (mmol/L)	8.47 ± 3.43	7.54 ± 3.19	<0.001*
2hPG (mmol/L)	13.01 ± 4.36	12.01 ± 4.30	<0.001*
HbA1c (%)	9.43 ± 2.33	8.65 ± 2.36	0.049*
Total cholesterol (mmol/L)	5.49 ± 1.02	5.43 ± 0.96	0.341
Triglycerides (mmol/L)	2.21 ± 1.27	2.13 ± 1.03	0.254
HDL-C (mmol/L)	1.30 ± 0.31	1.32 ± 0.32	0.297
LDL-C (mmol/L)	2.81 ± 0.46	2.91 ± 0.45	0.001*
sRAGE (pg/mL)	526.17 (381.96–798.33)	522.15 (360.79–739.80)	0.168

∗Significant results.
Numbers are given as 𝑛 (%).