RU28318, an Aldosterone Antagonist, in Combination with an ACE Inhibitor and Angiotensin Receptor Blocker Attenuates Cardiac Dysfunction in Diabetes
Figure 2
The effect of drugs given after ischemia on % recovery in cardiac function versus reperfusion time for (a) , (b) LVEDP, (c) , (d) , and (e) CF in control hearts. RUL: RU28318; Capt: Captopril; Los: Losartan; Triple: RU28318 + Captopril + Losartan; : left ventricular developed pressure; LVEDP: left ventricular end-diastolic pressure; : positive derivative of pressure; : negative derivative of pressure; CF: coronary flow; %: % recovery: (reperfusion/baseline) × 100.
