Association of the HLA-DQA1 and HLA-DQB1 Alleles in Type 2 Diabetes Mellitus and Diabetic Nephropathy in the Han Ethnicity of China

Table 1

Clinical and biochemical parameters of the controls and diabetic subjects.

	T2DM patients
	Without DN group	DN group	Controls
𝑁	100	210	100
Age	57.8 ± 9.5	58.1 ± 8.7	57.5 ± 4.7
Gender (male/female)	47/53	105/105	50/50
Age at diagnosis of DM (years)	53.3 ± 10.5	51.7 ± 8.3^#	—
Diabetes duration (years)	13.2 ± 2.7	16.1 ± 4.5^†	—
BMI (kg/m^2)	25.5 ± 3.6*	25.8 ± 4.0*	23.1 ± 3.8
Hypertension (%)	47 (47%)*	152 (72.4%)^†*	23 (23%)
SBP (mmHg)	136.2 ± 16.5*	144.1 ± 17.6^†*	130.4 ± 15.7
DBP (mmHg)	80.7 ± 9.5*	83.2 ± 9.6^†*	76.1 ± 8.9
FPG (mmol/L)	9.3 ± 5.8*	9.5 ± 6.4*	5.1 ± 3.7
HbA1c (%)	9.2 ± 4.3*	9.3 ± 5.7*	5.2 ± 2.8
Triglyceride level (mmol/L)	1.4 ± 0.7*	1.8 ± 0.9^†*	1.1 ± 0.6
Total cholesterol level (mmol/L)	4.8 ± 1.2	4.9 ± 1.4	4.7 ± 1.5

Data are expressed as means ± SD and 𝑛 (%); ^∗𝑃<0.01 versus controls; ^#P < 0.05 versus without DN group; ^†𝑃<0.01 versus without DN group.