Association of the HLA-DQA1 and HLA-DQB1 Alleles in Type 2 Diabetes Mellitus and Diabetic Nephropathy in the Han Ethnicity of China

Table 6

Frequency of HLA-DQB1 alleles in T2DM patients with and without DN.

HLA-DQB1 allele	DN0 (𝑛=100)		DN1 (𝑛=210)
	PN	AF	PN	AF	𝜒^2	𝑃
DQB1*0201	18	0.09	40	0.095	0.044	0.834
DQB1*0301	20	0.10	44	0.105	0.033	0.855
DQB1*0302	32	0.16	82	0.195	1.121	0.290
DQB1*0303	41	0.205	91	0.217	0.110	0.740
DQB1*0401	16	0.08	37	0.088	0.114	0.736
DQB1*0501	29	0.145	25	0.058	12.45	0.004^(*)
DQB1*0601	24	0.12	65	0.155	1.332	0.249
DQB1*0602	20	0.1	36	0.086	0.337	0.562

PN: positive number; AF: antigen frequency; DN0: without DN group; DN1: DN group; ^(∗)𝑃 value < 0.05.