Review Article

Early Life Factors and Type 2 Diabetes Mellitus

Figure 3

Lactation and insulin resistance. It has been found that both early weaning and overfeeding by more milk intake may lead to insulin resistance in later life. Maternal stress, obesity, hyperglycemia, and even smoking during lactation might also cause reduced insulin sensitivity in the offspring, which suggest that the breast milk can be the “agent,” transferring altered levels of hormones, insulin, or fatty acid contents from maternal circulation to neonate.
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