Cardiopulmonary Profile in Streptozotocin-Induced Type 1 Diabetic Rats during Systemic Endotoxemia

Table 1

Effects of LPS administration (15 mg/kg, i.v.) on arterial blood gas in normal and diabetic rats.

	pH	PaCO2 (mmHg)	PaO2 (mmHg)	SaO2 (%)
NS	7.38 ± 0.01	42.03 ± 1.08	106.95 ± 2.28	97.82 ± 0.17
NL	7.40 ± 0.02	30.66 ± 1.99^a	122.09 ± 5.93^a	98.77 ± 0.21^a
SS	7.41 ± 0.01	41.96 ± 0.92	91.40 ± 2.64^a	96.93 ± 0.37^a
SL	7.43 ± 0.01	30.63 ± 1.58^c	106.50 ± 3.55^b,c	97.96 ± 0.23^b,c

PaCO₂: arterial carbon dioxide tension; PaO₂: arterial oxygen pressure tension; SaO₂: oxygen saturation. Data are expressed as means ± S.E.M of 8 rats per group. ^aP < 0.05, compared with the NS group; ^bP < 0.05, compared with the NL group; ^cP < 0.05, compared with the SS group (one-way ANOVA).