Skin Autofluorescence Relates to Soluble Receptor for Advanced Glycation End-Products and Albuminuria in Diabetes Mellitus

Table 2

Skin autofluorescence and novel biochemical parameters.

	T1DM	T2DM	Controls	ANOVA
	(𝑛=47)	(𝑛=41)	(𝑛=20)	𝑃 value
AF (AU)	2.39±0.54^b	2.63±0.73^c	1.96±0.33	<0.0001
sRAGE (ng/L)	1250±627	1040±567	1163±537	0.26
vWF (%)	114±48	127±56^a	93±25	0.038
sICAM-1 (𝜇g/L)	269±89	266±79	223±82	0.10
sVCAM-1 (𝜇g/L)	907±498^c	816±271^c	392±91	<0.0001
P-selectin (𝜇g/L)	113±36^b	101±35^c	145±52	0.0004
E-selectin (𝜇g/L)	29±16^a	36±16	41±15	0.011

Results are means ± SD, or means with 1 SD range. One-way ANOVA was performed, with 𝑃 values in the last column of the table. Statistical significance expressed by LSD post hoc test between DM and control persons: ^a𝑃<0.05, ^b𝑃<0.01, and ^c𝑃<0.001.
Abbreviations: AF: autofluorescence; AU: arbitrary unit; sRAGE: soluble receptor for advanced glycation end-products; vWF: von Willebrand factor; sICAM: intercellular adhesion molecule; sVCAM: vascular cell adhesion molecule.