The Missing Heritability in T1D and Potential New Targets for Prevention

<table>TRAV and TRBV polymorphic positions shown on a TCR/pMHC complex structure. Polymorphic positions are red, TCR<i>α</i> is light blue, TCR<i>β</i> is blue, peptide is magenta, and MHC is green. Structure shown is HA1.7 TCR/HA peptide/HLA-DR4 (Protein Data Bank [<a href="/journals/jdr/2013/737485/#B74">43</a>] ID 1J8H). The figure was generated using PyMOL (<a href="http://www.pymol.org/">http://www.pymol.org/</a>).</table>

Journal of Diabetes Research

fig4

Figure 4

Figure 4: The Missing Heritability in T1D and Potential New Targets for Prevention 