Journal of Diabetes Research / 2013 / Article / Tab 2

Review Article

Cardiovascular Changes in Animal Models of Metabolic Syndrome

Table 2

Main cardiovascular findings in chemically induced animal models of metabolic syndrome.

ModelsCardiovascular changes

MSG-induced SHR(i) High blood pressure levels
(ii) Reduced heart rate variability
(iii) Decreased spontaneous baroreflex sensibility
(iv) Increased cardiac sympathovagal balance
(v) Increased systolic arterial pressure variability

Streptozotocin administration(i) Systolic and diastolic dysfunction at rest
(ii) Reduced capacity for cardiac adjustment to
  volume overload
(iii) Reduction in baroreflex-mediated
  bradycardia and tachycardia
(iv) Impairment in cardiac vagal tone

MSG: monosodium glutamate; SHR: spontaneously hypertensive rat.