Cardiovascular Changes in Animal Models of Metabolic Syndrome

Table 2

Main cardiovascular findings in chemically induced animal models of metabolic syndrome.

Models	Cardiovascular changes
MSG-induced SHR	(i) High blood pressure levels
	(ii) Reduced heart rate variability
	(iii) Decreased spontaneous baroreflex sensibility
	(iv) Increased cardiac sympathovagal balance
	(v) Increased systolic arterial pressure variability
Streptozotocin administration	(i) Systolic and diastolic dysfunction at rest
	(ii) Reduced capacity for cardiac adjustment to; volume overload
	(iii) Reduction in baroreflex-mediated; bradycardia and tachycardia
	(iv) Impairment in cardiac vagal tone

MSG: monosodium glutamate; SHR: spontaneously hypertensive rat.